EVAL3DPET

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Programs for the Evaluation of 3D PET Reconstruction Algorithms

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Medical Image Processing Group, 19 Department of Radiology, 20 University of Pennsylvania

1 45 EVAL3DPET is a set of programs designed to statistically evaluate 3D 46 PET reconstruction algorithms. The software comprises of tools for 3D 43 phantom and projection data generation, evaluation and statistical 45 comparison, and it includes some fully 3D reconstruction algorithms. 4

1 3f The EVAL3DPET programming system is designed to be capable of: 5

Generating phantom and projection data based on a realistic 3D PET 44 scanner model. The phantoms are random samples from a statistically 42 described ensemble of 3D images with 69 ellipsoid features (cold, 40 normal and hot) ranging from small (4 mm) to large (40 mm). The 45 projection data generation takes into account detector field-of-view 2f blurring and a realistic 3D PET noise model. 1 14
Evaluating for 3a structural accuracy, hot spot detectability and cold spot 10 detectability. 1 37
The evaluation program also calculates a training 40 figure-of-merit, that can be used for optimizing reconstruction 3f techniques. Statistically comparing the efficacy of a pair of 2c reconstruction techniques using the t-test. 9

1 45 Included, as examples, are the ART and EM reconstruction techniques, 47 both implemented using traditional voxels and also using the so-called 41 "blob" basis functions. Our implementations of ART use a special 47 data-access ordering (of projection rays) to achieve fast convergence. 3d The EM algorithms support both attenuated and non-attenuated 11 projection data. 4

1 25a EVAL3DPET will be made available (on a CD ROM) to all who request it at the cost of reproduction and mailing of the C source code, manual and example data files. The programs were developed using the C language (K&R), under a UNIX operating system, and they have been tested on SPARCstations (SUN) and Silicon Graphics machines. There is a charge of US$150.00 (checks only) for providing this service. (For overseas mailing add another US$50.00 if air mail delivery is required.) Please make the check payable (in US currency drawn on a US bank) to RADIOLOGY ASSOCIATES and send it with your order to: 1 d

a
12 Ms. Mary Blue
23 Medical Image Processing Group
2f Dept. of Radiology - Univ. of Pennsylvania
1d Blockley Hall, 4th Floor
16 418 Service Drive
20 Philadelphia, PA 19104-6021
a U.S.A.
19 Tel: +1-215-662-6780
19 Fax: +1-215-349-8426
1b email: mary@mipg.upenn.edu b
e

1 47 By purchasing the EVAL3DPET software, the recipient agrees to abide by 15 the following terms: 5

EVAL3DPET shall not be redistributed in any way. 1 4a
EVAL3DPET is not a patient-care tool and it is not approved by the 30 United States Federal Drug Administration. 1 4e
While every effort has been made to correct all known bugs, EVAL3DPET is 45 provided "as is" with no warranty whatsoever. As such, the recipient 45 agrees not to hold the authors responsible for any problems they may 1f encounter with the software. 1 4c
The recipient agrees to purchase EVAL3DPET with the explicit knowledge 31 that the authors do not offer technical support. 6

1 1a

Medical Image Processing Group, Department of Radiology, University of Pennsylvania Health System

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