(1) Introduced iterative image reconstruction methods in CT (1970, Gordon, Bender, Herman).
   (2) 2D image reconstruction software from MIPG transferred to first GE CT scanner (1975, Rowland, Herman, et al). 

   (3) Laid the foundation for 3D surface rendering in medical imaging (1979, Herman, Liu).  

   (4) First published 3D image segmentation algorithm (1977, Liu; 1979, Udupa, Srihari, Herman).  

   (5) First published 3D skeletonization method (1979, Udupa, Srihari, Yau).  

   (6) First to develop software packages for 3D imaging, which were distributed widely, even in those days of non - standard platforms (1980, DISPLAY; 1982 - DISPLAY82, Udupa, Herman, Frieder, Yau, et al).
   (7) First to transfer 3D imaging to industry, GE CT/T8800 scanner (1980, 1981, Udupa), first 3D imaging demonstrated at RSNA (1981).
   (8) First development of image reconstruction methods and software for time-varying 3D images and cone beam data. Many aspects of this work were far ahead of their time. This software was used by the Dynamic Spatial Reconstructor scanner of the Mayo Clinic (1980 - Herman, Lewitt, et al).
   (9) DISPLAY and DISPLAY82 developed by MIPG were installed at Mayo Clinic whose researchers were using these software packages until 1985 when they developed their own package called, Analyze (1980, 1981, Udupa).
  (10) Laid the foundation for 3D and higher-dimensional digital geometry and topology (1981, Artzy, Frieder, Herman; 1981, Udupa, 1982, Udupa, Srihari, Herman).
  (11) First published paper on brain MR image processing and visualization (1981, Herman, Udupa, Lauterbur, et al).
  (12) First to demonstrate medical applications of 3D imaging in several areas: neuro (1980, Coin, Herman), craniofacial (1979, Hemmy, Herman), heart (1983, Axel, Herman, Udupa, Bottomley) and joint kinematics (1984, Roberts, Udupa).
  (13) Early image registration algorithm published at the same time the Pelizzari et al method was published (1989, Toennies, Udupa, Herman).
  (14) Introduced shape-based interpolation (1990, Raya, Udupa).
  (15) Introduced the fuzzy connectedness and live-wire family of methods to image segmentation, which have had a significant impact on the image segmentation literature (1995, Udupa, Samarasekera).
  (16) Introduced special image grids with smooth spherical lobs for image reconstruction (1990, 1992, Lewitt, Matej).  

  (17) Forerunners in transferring iterative algorithms from research labs to clinical nuclear medicine (1999, Lewitt, Matej).
  (18) Developed the fastest surface rendering technique (1991, Udupa, Odhner).  

  (19) First published paper to suggest the use of 3D imaging for surgery simulation through interactive 3D object editing (1982, Udupa; 1984, Udupa, et al).
  (20) 3DVIEWNIX, a software system designed, developed, maintained and distributed by us for 3D image processing, visualization, analysis, has had a significant impact in medical imaging and other areas. This system has over 40 person years of work into it so far. (1994, Udupa, et al).
  (21) We organized the first conference on 3D imaging (1988, 1990, Herman, Udupa).